Nano silver effects on developing airway: a histological evaluation

Authors

  • Asefe Kamrani Department of Biology, Parand Branch, Islamic Azad University, Parand, Iran
  • Mitra Heydari Nasrabadi Department of Biology, Parand Branch, Islamic Azad University, Parand, Iran
  • Sajjad Shabnezhad Clinical Education Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

DOI:

https://doi.org/10.22034/LSSJ.2023.1.55

Abstract

Introduction: Nano silver is widely used for its antibacterial effect. Nanoparticles have toxicity effects in the environment. People who are at risk of nanomaterials may have the effect of nanoparticles on the environment and also they will be discharged due to toxic environmental contamination. The nanoparticles may have altered the immune system and blood cells and improper use of them is harmful to the body. Silver nanoparticles can enter the bloodstream and then spread in the placenta, therefore also affecting the development of organs.
Methods: Pregnant Wister rats were administrated with concentrations of 125, 750, and 1500 mg/kg/day silver colloid nanoparticles via gavage in and histologically evaluated the airway development at the nineteenth day of gestation.
Result: Our finding reveals that a noted delay in lung embryonic development occurred in all three concentrations 125,750 and 1500 mg/kg/day.
Conclusion: In this study, possible teratogenic effects of silver nanoparticles appear in different stages of rat lung embryogenesis.

Downloads

Published

2023-04-28

How to Cite

Kamrani, A., Heydari Nasrabadi, M., & Shabnezhad, S. (2023). Nano silver effects on developing airway: a histological evaluation. Life Sciences Student Journal, 1(1), 7–10. https://doi.org/10.22034/LSSJ.2023.1.55

Issue

Vol. 1 No. 1 (2023)

Section

Articles

License

 Publisher's Own License

This work is licensed under the publisher's own license, which allows for sharing and use under specific conditions. Attribution is required; users must give appropriate credit to the original creator. Additionally, this license includes a No Commercial Usage clause, meaning that the work cannot be used for commercial purposes or for profit. Users are encouraged to share and adapt the content non-commercially, provided they adhere to these guidelines. Please ensure that you respect the terms of this license to promote a collaborative and respectful use of the work.