The Impact of Gut Microbiome Changes on Health and Disease in Older Adults

Authors

  • Siamak Takesh University of Coimbra, Faculty of Sport Sciences and Physical Education, Coimbra, Portugal
  • Mohsen Parvani Ph.D. Student in Physical Activity and Health, Faculty of Sport Sciences and Physical Education, University of Coimbra, Coimbra
  • Ebrahim Banitalebi Full Professor Physical Education and Sport Science, Department of Sport Sciences, Shahrekord University, Shahrekord, Iran

DOI:

https://doi.org/10.22034/LSSJ.2025.134

Keywords:

Gut microbiome, aging, gut brain axis, Probiotics, Exercise

Abstract

The aging process can make physiological and functional changes that boost the susceptibility of chronic diseases through alterations in the gut microbiome’s composition and diversity. These alterations influence the immune system, metabolism, cognitive function, and other aspects of health. This review is designed to investigate how alterations in the gut microbiome are associated with aging-related conditions, including diabetes, cardiovascular diseases, Alzheimer’s disease, and metabolic disorders. In this paper we also highlight the bidirectional gut-brain axis and the mechanisms that control gut health. In addition, it discusses effective strategies like balanced nutrition, probiotics, physical activity, and stress management that can help improve gut microbiome diversity and benefit the health of older adults. The findings aim to contribute in the development of targeted interventions to mitigate the effects of age-related changes in the gut microbiome.

Downloads

Published

2025-02-15

How to Cite

Takesh, S., Parvani, M., & Banitalebi, E. . (2025). The Impact of Gut Microbiome Changes on Health and Disease in Older Adults. Life Sciences Student Journal, 3(1), 13–32. https://doi.org/10.22034/LSSJ.2025.134

Issue

Vol. 3 No. 1 (2025): Vol.3 No.1 (2025)

Section

Articles

License

 Publisher's Own License

This work is licensed under the publisher's own license, which allows for sharing and use under specific conditions. Attribution is required; users must give appropriate credit to the original creator. Additionally, this license includes a No Commercial Usage clause, meaning that the work cannot be used for commercial purposes or for profit. Users are encouraged to share and adapt the content non-commercially, provided they adhere to these guidelines. Please ensure that you respect the terms of this license to promote a collaborative and respectful use of the work.